Ihe mejupụtara, nkọwa, nyocha na ntuziaka

Ihe mejupụtara, nkọwa, nyocha na ntuziaka

afọ ruo afọ 18.

Achọpụtabeghị mmekọrịta ya na ọgwụ ndị ọzọ.

- ịbawanye mmepụta nke collagen ma gbochie mmetụta na-akpali akpali nke IL-1 na njikọ nke collagenase;

N'ime, 1 okpu. kwa ụbọchị, ọkacha mma n'ụtụtụ na nri, na-aṅụ 250 ml mmiri. Usoro ọgwụgwọ bụ ọnwa 6. Mmụba nke oge na usoro ọgwụgwọ ugboro ugboro ga-ekwe omume mgbe gị na dọkịta gbasasịrị.

- mezie njikọ nke macromolecules nke intercellular umi nke articular cartilage, bụ ihe na-akpali akpali nke njikọ nke macromolecules nke hyaline cartilage, yana periodontal anụ ahụ, na-egbochi eze ọnwụ.

Capsules (ụdị I), nke nwere okpu ọcha na ahụ ọcha na-enweghị isi nke akara "P300". Ihe dị n'ime capsules bụ tapawa aja aja.

ihe mgbakwunye : butylhydroxytoluene; silicon dioxide colloid na-edozi cartilage metabolism .

Ngwakọta mmanụ soybean na-adịghị mma ọgwụ herbal nke na-achịkwa metabolism na anụ ahụ cartilage.

- ịbawanye mmepụta nke ihe mgbochi nke plasminogenesis activator, si otú ahụ belata mmebi nke cartilage, ma n'ụzọ na-apụtaghị ìhè site na mkpali nke metalloproteinases, na site na ime ihe kpọmkwem na cartilage, na-eme ka mmebi nke proteoglycans, nke na-egbochi mbibi nke cartilage;

na mkpọ ọnya 15 ma ọ bụ 30 okpu; na mkpọ kaadiboodu 1 mkpọ.

usoro ọgwụgwọ mgbagwoju anya nke osteoarthritis nke ikpere na nkwonkwo hip nke ogbo I-III;

A naghị enye data na pharmacokinetics nke ọgwụ ahụ.

ọgwụgwọ adjuvant nke periodontitis.

N'ebe a na-echebe site na ìhè, na okpomọkụ nke 15-25 Celsius.
Nkọwa nke ọgwụ Piascledin 300 (capsules) dabere na ntuziaka gọọmentị, nke ndị nrụpụta kwadoro na 2011.

ihe mejupụtara capsule: titanium dioxide (E171); gelatin - mụbaa ọrụ nke na-agbanwe ihe na-eto eto β 1 (TGF) na chondrocytes, nke nwere mmetụta anabolic;

O nwebeghị ikpe gbasara ịdoụbiga mmanya ókè ruo taa.

Na-achịkwa usoro metabolic na anụ ahụ cartilage. Ọ nwere mmetụta mgbochi mkpali na analgesic na nkwonkwo. Na-enyere aka belata usoro mmebi ahụ na cartilaginous anụ ahụ nke nkwonkwo, na-ebelata ihe mgbu metụtara usoro a, ma weghachite ọrụ moto. N'ime nchọpụta nnwale, egosila na ọgwụ ahụ nwere mmetụta na-emeghachi omume na cartilage, na-akpali njikọ nke collagen na articular chondrocytes.

Ube oyibo mmanụ unsaponifiable compoundsunsaponifiable ogige nke soy bean mmanụ na ube oyibo mmanụ:

hypersensitivity n'otu n'otu na ihe na-arụ ọrụ na ihe ndị ọzọ nke ọgwụ ahụ;

Amabeghị ikpe nke ịdoụbiga mmanya ókè.

N'ọnọdụ ụfọdụ, gastralgia, flatulence, ọgbụgbọ, afọ ọsịsa, afọ ntachi, isi ọwụwa, iro ụra, mmeghachi omume nfụkasị (gụnyere erythema, urticaria, itching) ga-ekwe omume.

ihe inyeaka: MCC - 68 mg; povidone K25 (polyvinylpyrrolidone K25) - 45 mg; croscarmellose sodium - 20 mg; macrogol 6000 (PEG 6000) - 15 mg; magnesium stearate - 8.5 mg; talc - 1.5 mg Site na usoro iku ume: a na -amaghị ugboro ole - ụkwara ume ọkụ / ọria ụkwara ume ọkụ.

A kọwo ọrịa hypercholesterolemia, mana enwebeghị njikọ kpatara ya.

Nnyocha: ụbara ọkwa nke enzymes imeju; mmụba na ọkwa glucose ọbara; mmụba ọbara mgbali.

N'ime, ọkacha mma n'oge nri, na-aṅụ otu iko mmiri.

Mbadamba ụrọ nke nwere ihe nkiri Madaus GmbH, Germany.

 — <1/100, >1/1000; adịkarịghị - <1/1000,> 1/10000; adịkarịghị - <1/10000; ugboro amaghi.

Site na uche: ugboro ole a na-amaghị - mmebi anya.

Site na usoro ahụ ji alụso ọrịa ọgụ: a na -amaghị ugboro ole - mmeghachi omume nfụkasị (hypersensitivity).

 

07/29/2019

Ọ bụrụ na ọ dị mkpa, a na-emegharị usoro ọgwụgwọ ya na nkeji nke ọnwa 2. Ogologo oge na usoro ọgwụgwọ bụ onye dọkịta na-aga.

Absorption na eriri afọ tract - 90%, bioavailability - 25%, T 1/2  - 70 awa.

Mgbe ị na-eji ọgwụ ahụ na ndị ọrịa nwere nnabata glucose na-adịghị mma, oke ịba ọcha n'anya na ụkọ akụrụ, nlekọta ahụike dị mkpa.

Glucosamine sulfate Sodium Chloride nwere ikike ịre ahịa: MEDA Pharma GmbH & Co. KG, Benzstrasse 1, 61352 Bad Homburg, Germany.

Nkọwa nke ọgwụ DONA® (mbadamba mkpuchi ihe nkiri, 750 mg) dabere na ntuziaka gọọmentị, nke ndị nrụpụta kwadoro na 2019.

 

lactation;

1 tab. (750 mg) ugboro abụọ n'ụbọchị.

Mbadamba nkume ndị nwere ihe nkiri na-acha ọcha, nke nwere oval, na-acha ọcha.

Ịkwado ọgwụ ahụ dị mma.

Ebe mmepụta (adreesị ziri ezi): Lutticherstrasse, 5, 53842 Troisdorf, Germany/Lutticherstrasse, 5, 53842 Troisdorf, Germany.

Site n'akụkụ CCC: ugboro ugboro - ọkụ ọkụ; ugboro ole na-amaghị - obi arrhythmia, tachycardia.

Ọgwụgwọ: ịsacha afọ, ọgwụgwọ symptomatic.

ụmụaka na-erubeghị afọ 18 (n'ihi enweghị data ụlọ ọgwụ sayensị na ụdị ndị ọrịa a).  

Mbadamba mbadamba ihe nkiri, 750 mg. 60 ma ọ bụ 180 tab. n'ime karama PE nwere okpu snap, tinye ya na igbe kaadiboodu.

A machibidoro iji ọgwụ ahụ eme ihe n'oge ime na n'oge a na-enye nwa ara n'ihi enweghị data ụlọ ọgwụ sayensị metụtara ụdị ndị ọrịa a.

Site n'akụkụ nke metabolism na nri: amabeghị ugboro ole - njikwa ọrịa shuga ezughị oke.

(nke kwekọrọ na glucosamine sulfate 750 mg na sodium chloride 192 mg) Mmetụta na ikike ịkwọ ụgbọ ala, usoro. N'ime oge ọgwụgwọ, a ga-akpachara anya mgbe ị na-anya ụgbọ ala ma na-etinye aka na omume ndị nwere ike ịdị ize ndụ nke chọrọ nlebara anya na ọsọ nke mmeghachi omume psychomotor, n'ihi na. iji ọgwụ eme ihe na obere oge nwere ike ime ka dizziness.

DONA®: tab.  p.p.o  750 mg, Nke 180 - 180 pcs.  - fl.  PE - ngwugwu.  kaadiboodu.

Mgbe ejikọtara ya na NSAIDs , ọ na-eme ka mgbochi mkpali na analgesic mmetụta nke ikpeazụ.

Site na akpụkpọ anụ na anụ ahụ subcutaneous: ugboro ugboro - erythema, itching, ihe ọkụ ọkụ; ugboro ole na-amaghị - angioedema, urticaria.

Ọ bụrụ na enweghị nkwalite mgbe ọgwụgwọ gasịrị, ma ọ bụ mgbaàmà na-akawanye njọ, ma ọ bụ ihe mgbaàmà ọhụrụ apụta, ị kwesịrị ịkpọtụrụ dọkịta gị. Ekwesịrị iji ọgwụ ahụ mee ihe naanị dị ka ihe ngosi, usoro ntinye na ntinye nke egosipụtara na ntuziaka.

Osteoarthritis nke mpụta nkwonkwo na ọkpụkpụ azụ, osteochondrosis.

Na-abawanye nnabata nke tetracyclines, na-ebelata - penicillins semi-synthetic, chloramphenicol.

Dakọtara na NSAIDs , paracetamol na corticosteroids.

DONA ® nwere mmetụta mgbochi mkpali na analgesic, mejupụta ụkọ glucosamine endogenous, na-akpali njikọ nke proteoglycans na hyaluronic acid na mmiri synovial; na-abawanye permeability nke capsule nkwonkwo, na-eweghachi usoro enzymatic na sel nke akpụkpọ ahụ synovial na cartilage articular. Na-akwalite nhazi nke sọlfọ na usoro nke njikọ nke chondroitinsulfuric acid, na-eme ka ntinye nke calcium nkịtị na ọkpụkpụ ọkpụkpụ, na-egbochi mmepe nke usoro mmebi na nkwonkwo, na-eweghachi ọrụ ha, na-ebelata mgbu mgbu.

Tel: (495) 660-53-03; faksị: (495) 660-53-06.

Nsogbu izugbe: ọtụtụ mgbe - ike ọgwụgwụ; ugboro na-amaghị - edema / peripheral edema.

942 mg nke akụrụ na-adịghị ala ala;

Site na eriri afọ tract: ọtụtụ mgbe - afọ ọsịsa, afọ ntachi, ọgbụgbọ, flatulence, abdominal mgbu, dyspepsia; ugboro amaghị - vomiting.

Maka ozi ndị ọzọ na nkwupụta, biko kpọtụrụ: 109028, Russia, Moscow, Serebryanicheskaya nab., 29.

Ihe ize ndụ nke ịmalite mmeghachi ahụ nfụkasị ahụ na-abawanye na enweghị ndidi na nri mmiri.

Na ịkpachara anya: bronchial ụkwara ume ọkụ na ọrịa shuga mellitus; ndị ọrịa nwere allergies na nri mmiri (osisi, shellfish). Ọgwụ nwere 75.5 mg sodium kwa mbadamba, nke ekwesịrị iburu n'uche na ndị ọrịa na nri sodium a na-achịkwa.

Site na usoro ụjọ ahụ: ọtụtụ mgbe - isi ọwụwa, iro ụra; ugboro ole amaghi - ehighi ura, dizziness.

A naghị atụ aro ka ị were ụmụaka na-erubeghị afọ 18 n'ihi enweghị data sayensị maka ụdị ndị ọrịa a.

Ụbọchị nkwado: 29.07.2019

Mmeghachi omume ọjọọ kachasị emetụta na nchịkwa ọnụ bụ ọgbụgbọ, mgbu afọ, dyspepsia, flatulence, afọ ntachi na afọ ọsịsa. Mmetụta ndị a kọwara na-adịkarị nwayọọ ma na-adịte aka.

Nsogbu sistemu hepatobiliary: ugboro ole amabeghị - jaundice.

Adreesị edebanyere aha: 51101, Cologne, Germany/51101, Cologne, Germany.

N'akụkụ obe, a na-ahụ akwa abụọ: nke dị n'èzí na-acha ọcha, nke dị n'ime na-acha ọcha na-acha odo odo ma ọ bụ agba aja aja.

shei ihe nkiri: methacrylic acid na methyl methacrylate copolymer (1: 1) (Eudragit L12.5) - 1 mg; titanium dioxide gbajiri agbaji - 11.5 mg; ntụ ọka - 10.55 mg; methyl methacrylate, trimethylammonioethyl methacrylate chloride na ethyl acrylate copolymer (2: 0.2: 1) (Eudragit RL30D) - 4.5 mg; triacetin (glycerol triacetate) - 0.9 mg; macrogol 6000 (PEG 6000) - 0.55 mg na-akwalite mmetụta nke coumarin anticoagulants.

A kọwapụtara mmetụta nke mmetụta dị ka ndị a: ọtụtụ mgbe -> 1/10; ọtụtụ mgbe <1/10,>1/100; ugboro ugboro

Mmetụta mgbaàmà na-apụta 2-3 izu mgbe ejiri ọgwụ ahụ mee ihe. Usoro ọgwụgwọ kacha nta bụ izu 4-6.

Ọgwụ ahụ na-agbanwe ọrụ arụ ọrụ nke protein S-100 nke ụbụrụ ụbụrụ, ma na-emekwa ka ọrụ njikọta nke ụbụrụ na ọkwa niile nke usoro akwara ozi (cellular, intercellular, structural and systemic).

A na-ekesa protein S-100 n'ọtụtụ ebe na CNS ma bụrụ nke ezinụlọ Ca 2+ na-ejikọta protein. Protein na-achịkwa usoro ndị dị mkpa na ụbụrụ: ọgbọ na nduzi nke mkpali akwara, nnyefe mgbaàmà synaptik; mkpali nke ọdịiche na mmụba nke neurons; N'ọkwa sistemu, protein S-100 na-agbanwe oke nke ntinye na usoro mgbochi, na-emetụta ọrụ nke ụbụrụ nke ọma. N'ihi nke a, S-100 nwere nootropic, neuroprotective na neurotrophic mmetụta.

E gosiputara nnwale na ọgwụ:

  • na-egosi ọrụ nootropic site na imeziwanye nguzobe nke ebe nchekwa na ihe nlereanya nke amnesia reflex conditioned; nkwụghachi ụgwọ maka ịda mbà n'obi metụtara afọ nke usoro nchekwa oge dị mkpirikpi; ịkwalite plasticity synapti ogologo oge (ihe ndabere nke usoro cellular nke ebe nchekwa na mmụta);
  • normalizes ọnọdụ mmetụta uche na omume ụmụ anụmanụ (na-ebelata ihe ngosi nke somatovegetative nke nrụgide, na-eweghachi ọrụ nyocha-locomotor).

E gosikwara na ọgwụ ahụ nwere mmetụta neuroprotective na neuroreparative: ọ na-abawanye nguzogide anụ ahụ ụbụrụ na hypoxia na mmetụta nsị, ma nwee akpụkpọ anụ-stabilizing, mmetụta antioxidant. N'ime oge ọrịa strok ma ọ bụ post-traumatic, ọ na-achịkọta ihe nkwụnye ụgwọ intracellular na-arụ ọrụ na protein S-100 nke neurons mebiri emebi na ahụike, yana sel glial dị na mpaghara mebiri emebi. Ọ nwere mmetụta anxiolytic akpọpụta nke ọma (na-ewepụ nchekasị).

Site n'ịgbanwe ọrụ bioelectrical nke ụbụrụ, ọ nwere ike imetụta nhazi nke ụra.

Usoro nke ime ihe

Prospectus - ọnụahịa, nnweta na ụlọ ahịa ọgwụ

Prospectus - ntuziaka maka ojiji

E gosipụtara ọnụahịa nke ị nwere ike ịzụta Prospectus na Moscow. Ị ga-anata kpọmkwem ọnụ ahịa n'obodo gị mgbe ịgachara ọrụ ịnye ọgwụ n'ịntanetị:

Mmetụta nke usoro nyocha physico-chemical nke oge a (chromatography gas-mmiri, chromatography mmiri na-arụ ọrụ dị elu, chromatography-mass spectrometry) anaghị ekwe ka nyochaa ọdịnaya nke ihe na-arụ ọrụ nke nkwadebe Prospect na mmiri mmiri, akụkụ ahụ na anụ ahụ n'ihi Ngwakọta dị iche iche nke nkwadebe (lee ngalaba "Composition"), nke na-eme ka ọ ghara ikwe omume na nkà na ụzụ na-amụ ọgwụ pharmacokinetics.

Ngosipụta maka ojiji

E gosipụtara atụmanya maka ojiji na ndị okenye.

Nsogbu uche nke mmalite dị iche iche, gụnyere ndị mgbe nnukwu ihe mberede cerebrovascular gasịrị.

Contraindications

Mmụba onye uche na akụkụ nke ọgwụ.
Ụmụaka dị afọ ruo afọ 18.
ụkọ lactase, anabataghị lactose, glucose-galactose malabsorption.

Jiri n'oge ime na n'oge ara

Amụbeghị nchekwa nke iji Prospectus n'ime ụmụ nwanyị dị ime na n'oge ị na-enye nwa ara. Ọ bụrụ na ọ dị mkpa, ịṅụ ọgwụ ahụ kwesịrị iburu n'uche oke ihe ize ndụ / uru.

Usoro onunu ogwu na nchịkwa

Ebubeghi ihe ize ndụ maka ikewa mbadamba nkume n'ime akụkụ.

n'ime. N'otu oge - mbadamba 2 (na-edebe n'ọnụ ruo mgbe agbazere kpamkpam - ọ bụghị n'oge nri). Were ugboro 2 n'ụbọchị. Usoro ọgwụgwọ bụ ọnwa 6; ọ bụrụ na ọ dị mkpa, enwere ike ịmeghachi usoro ọgwụgwọ mgbe ọnwa 1-2 gachara.

Ọ bụrụ na enweghi ọganihu n'ime izu 4 mgbe mmalite ọgwụgwọ, ị kwesịrị ịkpọtụrụ dọkịta.

Mmetụta

Mmeghachi omume nwere ike ime nke mmụba n'otu n'otu na akụkụ nke ọgwụ ahụ.

N'ọnọdụ ndị a na-adịghị ahụkebe, ọgwụ ahụ nwere ike ịkpata ụra.

Ịṅụbiga mmanya ókè

N'ihe banyere ịṅụbiga mmanya ókè, ihe ngosi dyspeptic ga-ekwe omume n'ihi ihe ndị mejupụtara ọgwụ ahụ.

Mmekọrịta na ọgwụ ndị ọzọ

Edebeghị aha ikpe nke enweghị nkwekọrịta na ọgwụ ndị ọzọ.

ntụziaka pụrụ iche

Ngwakọta nke ọgwụ ahụ gụnyere lactose, yabụ, a naghị atụ aro ka ị nye ya ndị ọrịa nwere congenital galactosemia, glucose ma ọ bụ galactose malabsorption syndrome, ma ọ bụ enweghị ụkọ lactase congenital.

Mmetụta na ikike ịnya ụgbọ ala

N'ọnọdụ ndị na-adịghị ahụkebe, iro ụra nwere ike ime, yabụ ekwesịrị ịkpachara anya mgbe ị na-anya ụgbọ ala.

Ụdị mwepụta

Lozenges. Mbadamba ụrọ 20 na ngwugwu ọnya nke ihe nkiri PVC na foil aluminum. A na-etinye ngwungwu blister 5, yana ntuziaka maka ojiji ahụike n'ime mkpọ kaadiboodu.

Ọnọdụ nchekwa

Na okpomọkụ adịghị elu 25 Celsius C.
Debe ebe ụmụaka na-apụghị iru.

Kachasị mma tupu ụbọchị

Afọ 3.
Ejila ụbọchị ngafe gachara.

Ọnọdụ ezumike

Ewepụtara ya site na ndenye ọgwụ.

Ụlọ ọrụ iwu kwadoro n'aha ya na-enye akwụkwọ ndebanye aha na nzukọ na-anabata nkwupụta na mpaghara nke Russian Federation

OOO NPF MATERIA MEDICA JIJI;
Russia, 127473, Moscow, 3rd Samotechny uzo, 9.

Adreesị ebe a na-emepụta ngwaahịa ọgwụ

OOO NPF MATERIA MEDICA JIJI;
Russia, 454139, Chelyabinsk mpaghara, Chelyabinsk, St. Buguruslanskaya, 54.

Na ọmụmụ na cell membranes na-egosipụta mmadụ GABA, serotonin na dopamine anabata (GABA B1A / B2 , 5-HT 2B , 5-HT 2C , 5-HT 3 na D 3 , karị), e gosiri na ọgwụ na-abawanye ọnụ ọgụgụ nke complexes "ligand-receptor", ya bụ, ọ nwere ike imetụta ma inhibitory na ịgbalite usoro neurotransmitter. Site na ịhazi nguzozi nke ọkwa nke ndị isi neurotransmitters, ọgwụ ahụ na-akwado ọrụ ntinye nke ụbụrụ.

Mgbanwe na ike dị iche iche nke ọrụ bioelectrical nke ụbụrụ ụbụrụ, hippocampus na hypothalamus n'okpuru mmetụta nke Prospecta ka egosipụtara na nnwale.

E gosipụtara mmetụta nootropic nke ọgwụ ahụ na nyocha ụlọ ọgwụ na ọgwụgwọ ndị ọrịa na oge mgbake mbụ nke ọrịa strok ischemic. E gosipụtara mmụba nke ọrụ ọgụgụ isi nke ndị ọrịa dị ka Montreal Cognitive Assessment Scale (MoCA) si kwuo, nke na-enyocha mpaghara ọgụgụ isi dị iche iche (nleba anya na ntinye uche, ọrụ ndị isi, ebe nchekwa, asụsụ, nkà na-emepụta ihe na-ahụ anya, echiche nkịtị, agụta na nhazi). .

Enwere mweghachi nke ọrụ na ndụ kwa ụbọchị dịka ọkwa Barthel si dị, nke na-enyocha akụkụ ọrụ dị ka ikike iri nri, na-elekọta onwe ya n'adabereghị, gụnyere ịsa ahụ na uwe, ọrụ physiological (stool, urination), ikike ịkwaga. (site n'àkwà ruo oche na azụ), njem n'ala dị larịị na ịrịgo steepụ. Dị ka ule na ọrịa strok ndụ ndụ (SS-QOL) ọnụ ọgụgụ, ndị ọrịa gosiri ọganihu na ọtụtụ ndị na-egosi (okwu, ọhụụ, echiche, ọnọdụ, ngagharị, wdg). E gosipụtara normalization nke omume na ọnọdụ nke ndị ọrịa n'ụdị mbelata nke mgbakasị ahụ, mmụba na ọkwa nke ọrụ onwe onye, ​​mbelata nke ihe isi ike n'ịrụ ọrụ ụlọ kwa ụbọchị, na mmụba nke ọrụ mmekọrịta n'ime ezinụlọ.

Pharmacokinetics

Nọmba ndebanye aha na ụbọchị

LP-006717

Aha ahia

prospectus

Ụdị usoro onunu ogwu

Lozenges.

Ngwakọta

Ihe na-arụ ọrụ:
Antibodies na protein S-100 nke ụbụrụ, emechara dị ọcha, gbanwee - 10,000 IU *.

ihe mgbakwunye: lactose monohydrate (lactose), microcrystalline cellulose, magnesium stearate.

* UMD - nkeji nke ime mgbanwe.

Nkọwa

Mbadamba ụrọ cylindrical dị larịị, nwere ihe egwu na bevel sitere na ọcha ruo na ọ fọrọ nke nta ka ọ bụrụ ọcha.

N'akụkụ dị larịị nwere ihe egwu, a na-etinye ihe odide MATERIA MEDICA.

Otu ọgwụ ọgwụ

Nootropic ọgwụ.

Koodu mpaghara:: ATX

N06BX.

Njirimara ọgwụ

Pharmacodynamics


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